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政大機構典藏 > 理學院 > 神經科學研究所 > 期刊論文 > Item 140.119/65229

Please use this identifier to cite or link to this item: https://nccur.lib.nccu.edu.tw/handle/140.119/65229

Title:	An expedient synthesis of honokiol and its analogues as potential neuropreventive agents
Authors:	Tripathi, Subhankar;Chan, Ming-Huan;Chen, Chinpiao 詹銘煥
Contributors:	神科所
Keywords:	Honokiol;Neuropreventive;Parkinson’s disease;Suzuki–Miyaura cross coupling;Claisen rearrangement
Date:	2012.01
Issue Date:	2014-04-09 17:17:29 (UTC+8)
Abstract:	An efficient synthesis of honokiol with Suzuki–Miyaura cross coupling obtained an overall yield of 45%. The proposed approach successfully synthesized several structurally similar alkyl, alkenyl and alkynyl analogues, seven of which showed potential neuropreventive activity against MPP+-induced and CHP/TBHP oxidative stress induced neuroblastoma cell death.
Relation:	Bioorg Med Chem Lett,22(1), 216-221
Source URI:	http://dx.doi.org/10.1016/j.bmcl.2011.11.030
Data Type:	article
Appears in Collections:	[神經科學研究所] 期刊論文

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