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    題名: Use of a Modified Spatial-Context Memory Test to Detect Amnestic Mild Cognitive Impairment.
    作者: 楊建銘
    Yang, Chien-Ming;Wang, Hsuan-Min;Kuo, Wan-Chin;Huang, Chin-Chang;Kuo, Hung-Chou
    貢獻者: 心理系
    關鍵詞: Alzheimer disease;Amnesia;Biology;Cognitive neurology;Cognitive neuroscience;Cognitive psychology;Dementia;Diagnostic medicine;Medicine;Memory;Mental health;Neurological Disorders;Neurology;Neuroscience;Psychiatry;Psychology;Research Article;Test evaluation
    日期: 2013.02
    上傳時間: 2013-12-26 17:24:08 (UTC+8)
    摘要: In this study we sought to differentiate participants with amnestic mild cognitive impairment (a-MCI) from those with mild dementia of Alzheimer’s type (m-DAT) and normal controls by modifying an existing test of spatial context memory (SCMT) designed so as to evaluate the function of brain regions affected in early m-DAT. We found that participants with a-MCI had better total scores on our modified SCMT than those with m-DAT. Furthermore, the locational memory subtest was able to discriminate between those with a-MCI and m-DAT. Additionally, compared with other screening tests, our spatial context memory test showed high sensitivity and specificity in discerning those with a-MCI from the normal population but, was relatively ineffective in discriminating a-MCI patients from those with m-DAT. We conclude that our modified test of SCMT is an effective tool for discriminating a-MCI from m-DAT and does so by detecting differences in locational memory.
    關聯: PLoS ONE, 8(2), 1-8
    資料類型: article
    DOI 連結: http://dx.doi.org/10.1371/journal.pone.0057030
    DOI: 10.1371/journal.pone.0057030
    顯示於類別:[心理學系] 期刊論文

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