政大機構典藏-National Chengchi University Institutional Repository(NCCUR):Item 140.119/55525

English | 正體中文 | 简体中文 | Post-Print筆數 : 27 | 全文笔数/总笔数 : 114205/145239 (79%)
造访人次 : 52611149 在线人数 : 856

RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.

政大機構典藏 > 理學院 > 神經科學研究所 > 國科會研究計畫 > Item 140.119/55525

请使用永久网址来引用或连结此文件: https://nccur.lib.nccu.edu.tw/handle/140.119/55525

题名:	骨形成蛋白於神經肌肉系統功能之研究
其它题名:	Role of Bone Morphogenetic Proteins in the Neuromuscular System
作者:	王培育
贡献者:	國立政治大學神經科學研究所行政院國家科學委員會
关键词:	基礎醫學;骨形成蛋白;神經肌肉系統
日期:	2009
上传时间:	2012-11-15 11:23:59 (UTC+8)
摘要:	The naturally occurring cell death of developing motor neurons is considered to be guided by the influence of their peripheries (Hamburger, 1934, 1958). Skeletal muscle cells have been implicated as a key source of peripheral-derived survival factors, as the absence of them causes a near total loss of developing motor neurons (Grieshammer et al., 1998). Many neuronal cell types are controlled by a small number of survival factors, with the genetic deletion of a single factor leading to a profound loss of neurons (Lindsay, 1996). Motor neurons, in contrast, appear to be controlled by numerous survival factors. The null mutation of a single, or even multiple, factors only leads to partial loss of motor neurons (Liu and Jaenisch, 2000; Oppenheim et al., 2000; Oppenheim et al., 2001). This may indicate that there are distinct subpopulations of motor neurons (Oppenheim et al., 2000). Equally, it implies that muscle fibers produce more than one regulator of motor neurons, as the consequence of the genetic deletion of them type is more profound than the deletion of any growth factor.
關聯:	基礎研究學術補助研究期間:9810~ 9907 研究經費:1250仟元
数据类型:	report
显示于类别:	[神經科學研究所] 國科會研究計畫

文件中的档案:

档案	大小	格式	浏览次数
982320B004003MY2[1].pdf	152Kb	Adobe PDF2	1111	检视/开启

在政大典藏中所有的数据项都受到原著作权保护.

社群 sharing

著作權政策宣告 Copyright Announcement

1.本網站之數位內容為國立政治大學所收錄之機構典藏，無償提供學術研究與公眾教育等公益性使用，惟仍請適度，合理使用本網站之內容，以尊重著作權人之權益。商業上之利用，則請先取得著作權人之授權。
The digital content of this website is part of National Chengchi University Institutional Repository. It provides free access to academic research and public education for non-commercial use. Please utilize it in a proper and reasonable manner and respect the rights of copyright owners. For commercial use, please obtain authorization from the copyright owner in advance.

2.本網站之製作，已盡力防止侵害著作權人之權益，如仍發現本網站之數位內容有侵害著作權人權益情事者，請權利人通知本網站維護人員(nccur@nccu.edu.tw)，維護人員將立即採取移除該數位著作等補救措施。
NCCU Institutional Repository is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff(nccur@nccu.edu.tw). We will remove the work from the repository and investigate your claim.

数据加载中.....