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    Title: 利用神經心理作業初探臺灣地區海洛因戒治者之認知功能研究
    The cognitive function research of the abstinent heroin users in Taiwan by using neuropsychological task
    Authors: 黃華妮
    Contributors: 許文耀
    黃華妮
    Keywords: 海洛因
    注意力偏誤
    執行功能
    成癮嚴重度
    Date: 2009
    Issue Date: 2011-10-11 16:55:33 (UTC+8)
    Abstract: 本研究主要是利用國內的海洛因戒治者,透過神經心理作業探討長期使用海洛因對於個體在注意力偏誤、轉換彈性和抑制能力上的影響。
    根據Robinson和Berridge(1993, 2003)的理論認為成癮嚴重度越高,藥物相關線索的注意力偏誤越明顯;然而,根據Di Chiara(2000)提出關於整合誘因和習慣的觀點,認為成癮的注意力偏誤和趨向行為會受到不同的成癮嚴重度(輕度或重度成癮)或成癮階段(早期或習慣化後期)而有不同的結果,另外,以往的執行功能損害也支持Robinson和Berridge(1993, 2003)成癮嚴重度的觀點,因此本研究企圖同時檢驗上述兩者觀點。

    本研究篩選111名台中戒治所和看守所的海洛因戒治者,分別根據不同的成癮嚴重程度分類方式分組(依賴嚴重度量表、不同頻率、施用方式),加上29名健康對照組,共140名受試均需完成自陳氏量表、紙筆測驗和各項神經心理測驗(Stroop叫色作業、威斯康辛卡片分類測驗、Go/No Go作業)。

    研究結果指出海洛因戒治者相較對照組確實在注意力偏誤、認知彈性轉換、以及反應抑制能力有損害的趨勢,而且似乎較符合Di Chiara(2000)提出整合誘因和習慣的觀點,認為成癮者的認知功能會與成癮嚴重度成負向關係。
    Reference: 中文部分
    行政院衛生署管制藥品管理局(2009)。台灣地區精神醫療院所通報海洛因藥物濫用個案件數。臺北市,行政院衛生署。
    法務部(1999):毒品危害防制條例參考資料彙編。臺北市,法務部。
    林柏君(2005)。影響毒品犯戒治成效相關因素之研究。國立中正大學犯罪防治研究所碩士論文。
    俞筱鈞(1994)。瑞文氏標準圖形推理測驗指導手冊。台北市:中國行為科學社。
    黃秀霜(2001)。中文年級認字量表:指導手冊。台北市:心理出版社。
    英文部分
    Bradley, B., Field, M., Mogg, K., & DeHouwer, J. (2004). Attentional and evaluative biases for smoking cues in nicotine dependence: component processes of biases in visual orienting. Behavior Pharmacology, 15, 29–36.
    Bruce, G., & Jones, B. T. (2006). Methods that measure attentional bias. Handbook on implicit cognition and addiction. Thousand Oaks, CA: SAGE, 135−149.
    Bradley, B. P., Mogg, K., Wright, T., & Field, M. (2003). Attentional bias in drug dependence: vigilance for cigarette-related cues in smokers. Psychological Addict Behaviors, 17, 66–72.
    Bechara, A., Noel, X., & Crone, E. A. (2006). Loss of willpower: abnormal neural mechanisms of impulse control and decision making in addiction. Handbook of implicit cognition and addiction. Thousand Oaks CA: SAGE, 215–32.
    Bearre, L., Sturt, P., Bruce, G., & Jones, B. T. (2007). Heroin-related attentional bias and monthly frequency of heroin use are positively associated in attenders of a harm reduction service. Addictive Behaviors, 32, 784–792.
    Chen, C. H., Chen, H., Lin, T. Y., Chou, H. H., Lai, T. J., Ferri, C. P., Gossop. M. (2008). Severity of heroin dependence in Taiwan: Reliability and validity of the Chinese version of the Severity of Dependence Scale (SDS [Ch]). Addictive Behaviors, 33, 1590–1593.
    Chen, Y. J., Ho, M. Y., Chen, K. J., Hsu, C. F., & Ryu, S. J. (2009). Estimation of premorbid general fluid intelligenceusing traditional Chinese reading performance in Taiwanese samples. Psychiatry and Clinical Neurosciences, 63, 500–507
    Cox,W. M., & Klinger, E. (1988). A motivational model of alcohol use. Journal Abnormal Psychology, 97, 168–180.
    Cox, W. M., Yeates, G. N., & Regan, C. M. (1999). Effects of alcohol cues on cognitive processing in heavy and light drinkers. Drug Alcohol Depend, 55, 85–89.
    Cox, W. M., Fadardi, J., & Pothos, E. M. (2006). The Addiction-Stroop Test: Theoretical Considerations and Procedural Recommendations. Psychological Bulletin, 132, 443−476.
    Clark, L., Robbins, T. W., Ersche, K. D., & Sahakian, B. J. (2006). Reflection impulsivity in current and former substance users. Biological Psychiatry, 60, 515–522.
    Di Chiara, G. (2000). Role of dopamine in the behavioural actions of nicotine related to addiction. European Journal of Pharmacology, 393, 295−314.
    Davis, P. E., Liddard, H., & McMillan, T. M. (2002). Neuropsychological
    deficits and opiate abuse. Drug Alcohol Depend, 67, 105–108.
    Darke, S., Sims, J., McDonald, S., & Wickes, W. (2000). Cognitive impairment among methadone maintenance patients. Addiction, 95(5), 687-695
    Field, M. (2005). Cannabis dependence and attentional bias for cannabis-related words. Behavior. Pharmacology, 16, 473–476.
    Field, M., Mogg, K., Zetteler, J., & Bradley, B. P. (2004). Attentional biases for alcohol cues in heavy and light social drinkers: the roles of initial orienting and maintained attention. Psychopharmacology (Berl.), 176, 88–93.
    Field, M., & Eastwood, B. (2005). Experimental manipulation of attentional bias increases the motivation to drink alcohol. Psychopharmacology (Berl.), 183, 350–357.
    Field, M., & Cox, W. M. (2008). Attentional bias in addictive behaviors: A review of its development, causes, and consequences. Drug and Alcohol Dependence, 97, 1–20
    Fu L. P., Bi, G. H., Zou, Z. T., Wang, W., Ye, E. M., Ma, L., Fan, M., & Yang, Z. (2008). Impaired response inhibition function in abstinent heroin dependents: An fMRI study. Neuroscience Letters, 438, 322–326
    Forman, S.D., Dougherty, G. G., Casey, B. J., Siegle, G. J., Braver, T. S., Barch, D. M., Stenger, V. A., Wick-Hull, C., Pisarov, L. A., & Lorensen, E. (2004). Opiate addicts lack error-dependent activation of rostral anterior cingulate. Biol Psychiatry, 55(5), 531-537.
    Fishbein, D. H., Krupitsky, E., Flannery, B. A., Langevin, D. J., Bobashev, G., Verbitskaya, E., Augustine, C. B., Bolla, K. I., Zvartau, E., Schech, B., Egorova, V., Bushara, N., & Tsoy, M. (2007). Neurocognitive characterizations of Russian heroin addicts without a significant history of other drug use. Drug and Alcohol Dependence, 90, 25–38.
    Franken, I. H. A. (2003). Drug craving and addiction: integrating psychological and neuropsychopharmacological approaches. Prog. Neuro- Psychopharmacol. Biol. Psychiatry, 27, 563–579.
    Franken, I. H. A., Kroon, L. Y., & Hendriks,V. M. (2000). Influence of individual differences in craving and obsessive cocaine thoughts on attentional processes in cocaine abuse patients. Addict. Behav, 25, 99–102.
    Franken, I. H. A., Kroon, L. Y., Wiers, R. W., & Jansen, A. (2000). Selective cognitive processing of drug cues in heroin dependence. J. Psychopharmacol, 14, 395–400.
    Goldstein, R. Z., & Volkow, N. D. (2002). Drug addiction and its underlying neurobiological basis: neuroimaging evidence for the involvement of the frontal cortex. Am. J. Psychiatry, 159, 1642–1652.
    Klinger, E., & Cox, W. M. (2004). Motivation and the theory of current concerns. Handbook of Motivational Counselling (Eds.), Wiley, Chichester, England.
    Kirby, K. N., Petry, N. M., & Bickel, W. K. (1999). Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls. Journal of Experimental Psychology General, 128, 78–87.
    Kirby, K. N., & Petry, N. M. (2004). Heroin and cocaine abusers have higher discount rates for delayed rewards than alcoholics or non-drug-using controls. Addiction, 99, 461–471.
    Lezak M. D. (1995). Neuropsychological assessment (3rd ed.). New York, Oxford University Press.
    Lundqvist ,T. (2005). Cognitive consequences of cannabis use: Comparison with abuse of stimulants and heroin with regard to attention, memory and executive functions. Pharmacology, Biochemistry and Behavior, 81, 319 – 330
    London E. D., Ernst, M., Grant, S., Bonson, K., & Weinstein, A. (2002). Obitofrontal cortex and human drug abuse: functional imaging. Cerebral Cortex, 10, 334–342.
    Lyvers, M., & Yakimoff, M. (2003). Neuropsychological correlates of opiod dependence and withdrawal. Addictive Behavior, 28, 605–611
    Moeller, F. G. & Dougherty, D. M. (2002). Impulsivity and Substance Abuse: What Is the Connection? Addict Disorder Their Treatment, 1, 3–10.
    Mogg, K., Field, M., & Bradley, B. P. (2005). Attentional and approach biases for smoking cues in smokers: an investigation of competing theoretical views of addiction. Psychopharmacology (Berl.), 180, 333–341.
    Miyake. A., Friedman, N. P., Emerson, M. J., Witzki, A. H., Howerter A., & Wager, T. D. (2000). The Unity and Diversity of Executive Functions and Their Contributions to Complex ‘‘Frontal Lobe’’ Tasks: A Latent Variable Analysis. Cognitive Psychology, 41, 49–100
    Marissen, M. A. E., Franken, I. H. A., Waters, A. J., Blanken, P., van den Brink, W., & Hendriks, V. M. (2006). Attentional bias predicts heroin relapse following treatment. Addiction, 101, 1306–1312.
    Mintzer, M. Z., & Stitzer, M. L. (2002). Cognitive impairment in methadone maintenance patients. Drug and Alcohol Dependence, 67, 41–51.
    Mintzer, M. Z., Copersino, M. L., & Stitzer, M. L. (2005). Opioid abuse and cognitive performance. Drug and Alcohol Dependence, 78, 225–230.
    Noël, X., Van der Linden, M., d`Acremont, M., Colmant, M., Hanak, C., Pelc, I., Verbanck, P., & Bechara, A. (2005). Cognitive biases towardalcohol-related words and executive deficits in polysubstance abusers with alcoholism. Addiction, 100(9), 1302-1309.
    Ornstein, T. J., Iddon, L. J., Baldacchino, A. M., Sahakian, B. J., London, M., Everitt, B. J., & Robbins, T. W. (2000). Profiles of cognitive dysfunction in chronic amphetamine and heroin abusers. Neuropsychopharmacology, 23, 113–126.
    Passetti, F., Clark, L., Mehta, M. A., Davis, P. E., Joyce, E., & King, M. (2008). Neuropsychological predictors of clinical outcome in opiate addiction. Drug and Alcohol Dependence, 94, 82-91
    Prosser, J., Cohen, L. J., Steinfeld, M., Eisenberg, D., London, E.D., & Galynker, I. I. (2006). Neuropsychological functioning in opiate-dependent subjects receiving and following methadone maintenance treatment. Drug Alcohol Depend, 84(3), 240-247.
    Pau, C. W. H., Lee, T. M. C., & Chan, S. F. (2002). The impact of heroin on frontal executive functions. Arch Clin Neuropsychol, 17, 663–670.
    Robinson, T. E., & Berridge, K. C. (1993). The neural basis of drug craving: an incentive-sensitization theory of addiction. Brain Res. Rev. 18, 247–291.
    Robinson, T. E., & Berridge, K. C. (2003). Addiction. Annu Rev Psychol 54, 25–53.
    Rossia, A., Daneluzzoa, E., Matteia, P., Bustinia, M., Casacchiaa, M. &
    Strattab, P. (1997). Wisconsin card sorting test and Stroop test
    performances in Schizophrenia: a shared construct. Neuroscience Letters
    226, 87–90
    Reynolds, B., Ortengren, A., Richards, J.B., de Wit, H. (2006). Dimensions of impulsive behavior: personality and behavioral measures. Pers. Individual Differences 40, 305–315.
    Rotheram-Fuller, E., Shoptaw, S., Berman, S. M., & London, E. D. (2004). Impaired performance in a test of decision-making by opiate-dependent tobacco smokers. Drug and Alcohol Dependence, 73, 79–86
    Tiffany, S. T. (1990). A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes. Psychological Rev, 97, 147–168.
    Verdejo, A., Toribio, I., Orozco, C., Puente, K. L., & Perez-Garcia, M. (2005). Neuropsychological functioning in methadone maintenance patients versus abstinent heroin abusers. Drug Alcohol Depend, 78, 283–288.
    Verdejo-Garcia, A., & Perez-Garcia, M. (2007). Profile of executive deficits in cocaine and heroin polysubstance users: common and differential effects on separate executive components. Psychopharmacology, 190, 517–530.
    Verdejo-Garcia, A. J., Perales, J. C., & Perez-Garcia, M. (2007). Cognitive impulsivity in cocaine and heroin polysubstance abusers. Addictive Behaviors 32, 950–966.
    Wiers, R. W., Bartholow, B. D., van den Wildenberg, E., Thush, C., Engels, R. C. M .E., Sher, K. J., Grenard, J., Ames, S. L., & Stacy, A. W. (2007). Automatic and controlled processes and the development of addictive behaviors in adolescents: a review and a model. Pharmacological Biochemistry Behaviors, 86, 263–283.
    Waters, A. J., & Feyerabend, C. (2000). Determinants and effects of attentional bias in smokers. Psychological Addictove Behaviors, 14, 111–120.
    Wilson, S. J., Sayette, M. A., & Fiez, J. A. (2004). Prefrontal responses to drug cues: a neurocognitive analysis. Natural Neuroscience, 7, 211–214.
    Yeomans, M. R., Javaherian, S., Tovey, H. M., & Stafford, L. D. (2005). Attentional bias for caffeine-related stimuli in high but not moderate or non-caffeine consumers. Psychopharmacology (Berl.), 181, 477–485.
    Description: 碩士
    國立政治大學
    心理學研究所
    95752015
    98
    Source URI: http://thesis.lib.nccu.edu.tw/record/#G0095752015
    Data Type: thesis
    Appears in Collections:[Department of Psychology] Theses

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