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    題名: Multiple sequence alignment modeling: methods and applications
    作者: 張家銘
    Chatzou, Maria;Magis, Cedrik;Chang, Jia-Ming;Kemena, Carsten;Bussotti, Giovanni;Erb, Ionas
    貢獻者: 資科系
    關鍵詞: multiple sequence alignments;protein alignments;alignment benchmarks;alignment reliability measures;RNA alignments;DNA alignments
    日期: 2015-11
    上傳時間: 2016-05-30 17:23:45 (UTC+8)
    摘要: This review provides an overview on the development of Multiple sequence alignment (MSA) methods and their main applications. It is focused on progress made over the past decade. The three first sections review recent algorithmic developments for protein, RNA/DNA and genomic alignments. The fourth section deals with benchmarks and explores the relationship between empirical and simulated data, along with the impact on method developments. The last part of the review gives an overview on available MSA local reliability estimators and their dependence on various algorithmic properties of available methods.
    關聯: Briefings in Bioinformatics
    資料類型: article
    DOI 連結: http://dx.doi.org/10.1093/bib/bbv099
    DOI: 10.1093/bib/bbv099
    顯示於類別:[資訊科學系] 期刊論文

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