政大機構典藏-National Chengchi University Institutional Repository(NCCUR):Item 140.119/92142

政大機構典藏-National Chengchi University Institutional Repository(NCCUR):Item 140.119/92142

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政大機構典藏 > 理學院 > 心理學系 > 學位論文 > Item 140.119/92142

請使用永久網址來引用或連結此文件: https://nccur.lib.nccu.edu.tw/handle/140.119/92142

題名:	阿朴嗎啡對中樞神經激胺的影響 Effects of apomorphine on central serotonergic system
作者:	王豐彬 Wang, Feng-Bin
貢獻者:	李小媛 Li, Xiao-Yuan 王豐彬 Wang, Feng-Bin
關鍵詞:	心理學 PSYCHIATRY PSYCHOLOGY
日期:	1984
上傳時間:	2016-05-05 17:24:27 (UTC+8)
摘要:	以高壓液態色層分析(HPLC)螢光測定生化分析同時量測背側縫合核及紋狀體中Tryp 序言壹論文摘要參第一章導論1 第一節文獻探討1 第二節研究目的8 第二章研究方法11 第一節實驗動物11 第二節藥品11 第三節儀器設備－－HPLC介紹 12 第四節手術－－腦部注射14 第五節組織切取20 第六節統計方法21 第三章實驗與結果23 第一節 APO對5-HT影響的詳細藥理機構23 第二節紋狀體DA突觸前接受器在APO對5-HT影響上所扮演的角色24 第三節 GABA在APO對5-HT影響中可能扮演的角色34 第四章討論49 第一節 APO對5-HT影響的詳細藥理機構49 第二節紋狀體DA突觸前接受器在APO對5-HT影響上所扮演的角色50 第三節 GABA在APO對5-HT影響中可能扮演的角色52 第四節 APO對5-HT影響的行為含意53 第五章結論55 參考文獻57 名詞對照表67 圖表目次圖一簡易神經通路4 圖二外在標準的HPLC螢光測定生化分析圖15 圖三背側縫合核的HPLC螢光測定生化分析圖16 圖四尾狀核的HPLC螢光測定生化分析圖17 圖五腹側縫合核的HPLC螢光測定生化分析圖18 圖六海馬迴的HPLC螢光測定生化分析圖19 Table 1. Effects of apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in dorsal raphe 25 Table 2. Effects of apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in caudate 26 Table 3. Effects of apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in median raphe. 27 Table 4. Effects of apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in hippocarnpus. 28 Table 5. Effects of 7 days 6-hydroxydopamine (caudate) and apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in dorsal raphe. 31 Table 6. Effects of 7 days 6-hydroxydopamine (caudate) and apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in caudate. 32 Table 7. Effects of 7 days 6-hydroxydopamine (caudate) and apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in median raphe. 35 Table 8 Effects of 7 days 6-hydroxydopamine (caudate) and apomorphine (3.0mg/kg, i.p.) on monoamine neurotransmitters and their precursors in hippocampus. 36 Table 9. Effects of apomorphine infusion (5ug,caudate) on monoamine neurotransmitters and their precursors in dorsal raphe. 37 Table 10. Effects of apomorphine infusion (5ug,caudate) on monoamine neurotransmitters and their precursors in caudate. 38 Table 11. Effects of apomorphine infusion (8ug,caudate) on monoamine neurotransmitters and their precursors in dorsal raphe. 39 Table 12. Effects of apomorphine infusion (8ug,caudate) on monoamine neurotransmitters and their precursors in caudate. 40 Table 13. Effects of apomorphine (8ug,caudate) on monoamine neurotransmitters and their precursors in mdeian raphe. 41 Table 14. Effects of apomorphine (8ug,caudate) on monoamine neurotransmitters and their precursors in hippocampus. 42 Table 15. Effects of apomorphine (3.0mg/kg, i.p.) and picrotoxin (4mg/kg, i.p.) on monoamine neurotransmitters and their precursors in dorsal raphe. 45 Table 16. Effects of apomorphine (3.0mg/kg, i.p.) and picrotoxin (4mg/kg, i.p.) on monoamine neurotransmitters and their precursors in caudate. 46 Table 17. Effects of apomorphine (3.0mg/kg, i.p.) and picrotoxin (4mg/kg, i.p.) on monoamine neurotransmitters and their precursors in median raphe. 47 Table 18. Effects of apomorphine (3.0mg/kg, i.p.) and picrotoxin (4mg/kg, i.p.) on monoamine neurotransmitters and their precursors in hippocampus. 48 附圖：Histology：Dye (Methylene Blue, 3mg/ml) infusion to caudate Neutral Red Staining. 65
描述:	碩士國立政治大學心理學系
資料來源:	http://thesis.lib.nccu.edu.tw/record/#B2002007106
資料類型:	thesis
顯示於類別:	[心理學系] 學位論文

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