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    题名: Functional connectivity for top-down modulation of visual activity strengthens visual short-term memory/ Neuropsychologia
    作者: Kuo, Bo-Cheng
    郭柏呈
    Yeh, Yei-Yu
    Chen, Anthony J.-W.
    D&apos, Mark;`Esposito
    贡献者: 心理系
    关键词: Functional connectivity;Event-related functional magnetic resonance imaging;Attention;Top-down control;Visual short-term memory
    日期: 2011-05
    上传时间: 2016-02-18 15:58:19 (UTC+8)
    摘要: Recent evidence has revealed that short-lived internal representations held in visual short-term memory (VSTM) can be modulated by top-down control via retrospective attention which impacts subsequent behavioral performance. However, the functional inter-regional interactions underlying these top-down modulatory effects are not fully characterized. Here we used event-related functional magnetic imaging to investigate whether the strength of functional connectivity between the frontal cortex and posterior visual areas varies with the efficacy of top-down modulation of memory traces. Top-down modulation was manipulated by the timing of retro-cuing (early or late) in a VSTM task. Univariate analyses revealed that more effective top-down modulation (early cueing vs. late cueing) increased activity in early visual areas. Importantly, coherency analyses revealed that top-down modulation produced stronger functional connectivity between frontal and posterior occipital regions. Also, participants with stronger functional connectivity exhibit better memory performance. These results suggest that augmented functional connectivity between frontal and posterior visual areas strengthens the VSTM representations of importance to behavioral goals.
    關聯: Neuropsychologia, 49(6), 1589-1596
    数据类型: article
    DOI 連結: http://dx.doi.org/10.1016/j.neuropsychologia.2010.12.043
    DOI: 10.1016/j.neuropsychologia.2010.12.043
    显示于类别:[心理學系] 期刊論文

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