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政大機構典藏 > 理學院 > 心理學系 > 期刊論文 > Item 140.119/142470

Please use this identifier to cite or link to this item: https://nccur.lib.nccu.edu.tw/handle/140.119/142470

Title:	Neural basis of operant behaviors maintained on the differential-reinforcement-of-low-rate (DRL) schedule in rodents
Authors:	廖瑞銘 Liao, Ruey-Ming Pattij, Tommy
Contributors:	心理系
Keywords:	Schedule-controlled behavior;Fronto-striatal circuitry;Timing;Behavioral inhibition;Impulsive action
Date:	2022-07
Issue Date:	2022-10-20 16:34:42 (UTC+8)
Abstract:	Various schedules of reinforcement have long been used in experimental psychology to establish and maintain operant behaviors. These reinforcement contingencies have also been widely applied in preclinical psycho- and neurobiology research. However, the differential reinforcement of low-rate response (DRL) schedule has received less attention than other schedules based on response ratios or different types of intervals. Hence, little is known about the neural basis of DRL schedule-controlled behavior. Herein, we review early and recent reports of rodent experiments utilizing brain lesions and intracranial drug infusions to respectively elucidate the neural substrates and neuropharmacological basis of DRL behavior. Overall, the available evidence implies that 1) certain cortical and subcortical areas are differentially involved in the DRL behavior and 2) disruption of dopamine or serotonin neurotransmission alters DRL behavior. We further identify remaining challenges in the field and suggest future work that will be helpful for understanding the neurobehavioral mechanisms of the DRL schedule of reinforcement.
Relation:	Brain Research Bulletin, Vol.185, pp.1-17
Data Type:	article
DOI 連結:	https://doi.org/10.1016/j.brainresbull.2022.04.003
DOI:	10.1016/j.brainresbull.2022.04.003
Appears in Collections:	[心理學系] 期刊論文

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