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    题名: Sleep extension improves glycemic control in Type 2 diabetes with obstructive sleep apnea
    作者: 楊建銘
    Yang, Chien-Ming
    Huang, Chih-Shan;Tan, Yong-Ning;Chang, Tsui-San;Sung, Jia-Ying
    贡献者: 心理系
    关键词: Glycated albumin;Obstructive sleep apnea;Sleep extension;Type 2 diabetes
    日期: 2021-10
    上传时间: 2022-08-23 15:08:50 (UTC+8)
    摘要: Background: The purpose of this study was to investigate whether sleep extension lowers blood glucose in patients with type 2 diabetes and chronic sleep restriction, and the moderating role of sleep apnea on the effect of sleep extension.

    Methods: This study enrolled 19 adults with type 2 diabetes and a sleep duration of less than 7 hours per night, of whom 16 (84.2 %) had obstructive sleep apnea. They were instructed to sleep at their usual time for 3 weeks as baseline, and then to increase their time in bed by 1 more hour per night for 3 weeks. Their sleep duration was recorded using actigraphy monitoring and sleep logs. Their fasting plasma glucose, glycated albumin, and glycated hemoglobin were measured before and after sleep extension.

    Results: Nine of the 19 (47.4 %) participants had a decrease in glycated albumin after sleep extension, and these participants had a significantly higher apnea-hypopnea index (AHI; p < 0.001). The participants with an AHI ≥ 30 times per hour were older (p = 0.04), had a shorter baseline total sleep time measured by actigraphy (p = 0.04), and had a more significant decrease in glycated albumin after sleep extension (p = 0.01). The AHI level was significantly correlated with the extent of decrease in glycated albumin after sleep extension (r = 0.72, p = 0.001).

    Conclusion: The current study showed the potential of 3-week sleep extension in decreasing blood glucose in patients with diabetes comorbid with severe obstructive sleep apnea and sleep deprivation.
    關聯: International Journal of Psychiatric Research, 4(5), pp.1-6
    数据类型: article
    DOI 連結: http://doi.org/10.33425/2641-4317.1110
    DOI: 10.33425/2641-4317.1110
    显示于类别:[心理學系] 期刊論文

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