政大機構典藏-National Chengchi University Institutional Repository(NCCUR):Item 140.119/120925

English | 正體中文 | 简体中文 | Post-Print筆數 : 27 | Items with full text/Total items : 113648/144635 (79%)
Visitors : 51682848 Online Users : 567

RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.

Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer

政大典藏 > College of Science > Graduate Institute of Neuroscience > Periodical Articles > Item 140.119/120925

Please use this identifier to cite or link to this item: https://nccur.lib.nccu.edu.tw/handle/140.119/120925

Title:	Anti-Mullerian hormone may be an autocrine regulator of motorneurons
Authors:	王培育 Wang, Pei-Yu Koishi, Kyoko McLennan, Ian S.
Contributors:	神科所
Keywords:	BMPRII;ALK2;ALK3;Axonal transport;Glia;Motoneuron
Date:	2004-09
Issue Date:	2018-11-20 09:18:41 (UTC+8)
Abstract:	The regulation of motoneuron survival is only partially elucidated. We have sought new survival factors for motoneuron by analyzing which receptors they produce. We report here that the type II bone morphogenetic receptor (BMPRII) mRNA is one of the most abundant receptor mRNAs in laser microdissected motoneurons. Motoneurons were intensely stained by an anti-BMPRII antibody, indicating the presence of BMPRII protein. One of its ligands (BMP6) supported the survival of motoneurons in vitro. BMP6 was produced by myotubes and mature Schwann cells and was retrogradely transported in mature motor axons. BMP6 thus joins a list of known Schwann-cell-derived regulators of motoneurons, which includes GDNF, CNTF, LIF and TGF-β2. The control of the production of these factors by Schwann cells and the direction of their movement in motor axons is diverse. This suggests that the multiplicity of motoneuron factors is because cells use different factors to regulate different aspects of motoneuron function.
Relation:	THE NEW ZEALAND MEDICAL JOURNAL, Vol.117, pp.1202
Data Type:	article
DOI link:	https://doi.org/10.1016/j.mcn.2007.01.008
DOI:	10.1016/j.mcn.2007.01.008
Appears in Collections:	[Graduate Institute of Neuroscience] Periodical Articles

Files in This Item:

File	Description	Size	Format
index.html		0Kb	HTML2	685	View/Open

社群 sharing

著作權政策宣告 Copyright Announcement

1.本網站之數位內容為國立政治大學所收錄之機構典藏，無償提供學術研究與公眾教育等公益性使用，惟仍請適度，合理使用本網站之內容，以尊重著作權人之權益。商業上之利用，則請先取得著作權人之授權。
The digital content of this website is part of National Chengchi University Institutional Repository. It provides free access to academic research and public education for non-commercial use. Please utilize it in a proper and reasonable manner and respect the rights of copyright owners. For commercial use, please obtain authorization from the copyright owner in advance.

2.本網站之製作，已盡力防止侵害著作權人之權益，如仍發現本網站之數位內容有侵害著作權人權益情事者，請權利人通知本網站維護人員(nccur@nccu.edu.tw)，維護人員將立即採取移除該數位著作等補救措施。
NCCU Institutional Repository is made to protect the interests of copyright owners. If you believe that any material on the website infringes copyright, please contact our staff(nccur@nccu.edu.tw). We will remove the work from the repository and investigate your claim.

Loading...