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Title:	Prevention of mother-to-child transmission: the key of hepatitis B virus elimination
Authors:	林志陵 Lin, Chih-Lin Kao, Jia-Horng
Contributors:	心理系
Date:	2018-03
Issue Date:	2018-09-18 15:54:50 (UTC+8)
Abstract:	More than half a century after the initial discovery, hepatitis B virus (HBV) is one of the most common viral infections in humans. With a global heterogeneous prevalence, the HBV epidemic remains a monumental threat of health. In Asia, most HBV patients acquire the virus perinatally or in early childhood and develop a life-long chronic infection [1]. The mechanisms of vertical HBV transmission include intrauterine infection and transmission during delivery [2]. For example, the prevalence of chronic HBV infection in the general population ranged 11–20% in Taiwan during 1980s [3]. Approximately, 40% of HBV carriers were born to HBsAg-positive mothers and 85–95% of newborns with HBV exposure consequently had chronic infection [4]. Thus, mother-to-child transmission (MTCT) during the perinatal period is the major transmission route of HBV in hyperendemic areas [1]. Prevention of MTCT is thus the most important strategy to reduce the global burden of HBV infection.
Relation:	Hepatology International, Volume 12, Issue 2, pp 94–96
Data Type:	article
DOI 連結:	https://doi.org/10.1007/s12072-018-9863-0
DOI:	10.1007/s12072-018-9863-0
Appears in Collections:	[心理學系] 期刊論文

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